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. 2016 Jun 20;44(13):6377–6390. doi: 10.1093/nar/gkw561

Figure 2.

Figure 2.

Structural comparison of TkoTrm11 and PfuTrm14 (PDB ID = 3TLJ). (A) Ribbon diagram of the overall structure of TkoTrm11. The three domains, NFLD, THUMP and RFM, and the rigid linker region are colored as in Figure 1A. (B) Ribbon diagram of the overall structure of PfuTrm14. The three domains, NFLD, THUMP and RFM, and a loop linker are colored cyan, orange, pink and grey, respectively. (C) Superimposition (obtaining by aligning respective Cα atoms) of the THUMP (red) and NFLD (green) domains of the TkoTrm11 structure onto that of the THUMP (orange) and NFLD (cyan) domains of the PfuTrm14 structure. (D) Superimposition (obtaining by aligning respective Cα atoms) of the TkoTrm11 RFM (slate blue) domain onto that of the PfuTrm14 RFM (pink) domain. (E) Line diagram of the overall structure based on the superimposed Cα atoms of THUMP and NFLD domains between the TkoTrm11 and PfuTrm14 structures. (F) Close-up view of the structural deviation of RFM domains (TkoTrm11, slate blue and PfuTrm14, pink) based on the superimposed Cα atoms of THUMP and NFLD domains between the TkoTrm11 and PfuTrm14 structures.