TABLE 2.
Target | Uninfected, clinically normal (n = 203)
|
Infected (n = 17)
|
Uninfected, active trachoma (n = 28)
|
||||||
---|---|---|---|---|---|---|---|---|---|
Mean | 95% CI | Median | Mean | 95% CI | Median | Mean | 95% CI | Median | |
IFN-γ | 0.48 | 0.43-0.52 | 0.48 | 1.48 | 1.01-2.16 | 1.16 | 0.71 | 0.53-0.94 | 0.73 |
TNF-α | 0.13 | 0.11-0.16 | 0.12 | 1.10 | 0.66-1.83 | 0.66 | 0.58 | 0.38-0.88 | 0.59 |
IL-1β | 0.11 | 0.09-0.14 | 0.09 | 0.91 | 0.52-1.58 | 1.09 | 0.89 | 0.48-1.65 | 0.68 |
IL-2 | 0.003 | 0.002-0.003 | 0.003 | 0.007 | 0.004-0.011 | 0.005 | 0.002 | 0.002-0.004 | 0.003 |
IL-4 | 0 | 0.0003 | 0.0002 | ||||||
IL-10 | 0.11 | 0.09-0.12 | 0.09 | 0.88 | 0.48-1.63 | 1.00 | 0.43 | 0.27-0.69 | 1.00 |
IL-12p35 | 0.03 | 0.02-0.03 | 0.028 | 0.03 | 0.02-0.03 | 0.025 | 0.02 | 0.02-0.03 | 0.021 |
IL-12p40 | 0.009 | 0.008-0.011 | 0.011 | 0.025 | 0.016-0.04 | 0.025 | 0.010 | 0.007-0.015 | 0.012 |
Perforin | 0.07 | 0.06-0.08 | 0.07 | 0.24 | 0.15-0.37 | 0.27 | 0.10 | 0.08-0.14 | 0.09 |
TGF-β2 | 0.04 | 0.03-0.04 | 0.04 | 0.04 | 0.03-0.06 | 0.04 | 0.03 | 0.02-0.04 | 0.03 |
MMP-1 | 1.12 | 0.98-1.30 | 1.25 | 0.59 | 0.32-1.08 | 0.59 | 0.94 | 0.66-1.33 | |
MMP-9 | 0.26 | 0.20-0.33 | 0.33 | 0.95 | 0.33-2.73 | 1.73 | 0.97 | 0.53-1.77 | 1.14 |
Collagen I | 0.12 | 0.11-0.14 | 0.13 | 0.15 | 0.10-0.24 | 0.14 | 0.15 | 0.10-0.22 | 0.16 |
Collagen I/MMP1 | 0.10 | 0.09-0.13 | 0.10 | 0.29 | 0.19-0.46 | 0.32 | 0.16 | 0.09-0.27 | 0.15 |