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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Biomaterials. 2016 Nov 28;120:81–93. doi: 10.1016/j.biomaterials.2016.11.035

Figure 9. Schematic showing directionality and speed dependence on contractility and adhesion across different cell lines.

Figure 9

(A and B) Migration directionality as a function of migration speed across different cell lines and perturbations. Colored regions represent classes of similar perturbations (Yellow: contractility and adhesion increases, Purple: large changes in contractility and Blue: contractility and adhesion decreases). Migration (C and D) directionality and (E and F) speed in MDA-MB-231 cells (black) and MTLn3 (grey) cells as a function of contractility and adhesion as measured by pS19-MRLC (contractility) and pY118-Pax (adhesion) signals. Axes ranges are not explicitly defined, but are function of the migration directionality, migration speed or staining intensity. Error bars are 95% confidence intervals.