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. 2004 Dec;72(12):7240–7246. doi: 10.1128/IAI.72.12.7240-7246.2004

FIG. 6.

FIG. 6.

Protection of IFNγ−/− mice by DO11 T cells. Panel A: Survival of IFN-γ−/− mice after infection with P30-OVA-transgenic cells (♦) or after adoptive transfer with DO11 cells and infection with parental Prugniaud parasites (○) or P30-OVA-transgenic cells (•). DO11 cells provided significant protection against parasites expressing secreted OVA. Panel B: Peritoneal exudate cells (cytospins) and liver histopathology demonstrate reduced parasite burden in DO11-transferred animals infected with P30-OVA-transgenic cells (right) versus parental Prugniaud strain parasites (left).