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. 2017 Feb 3;12(2):e0171366. doi: 10.1371/journal.pone.0171366

Fig 3. TRPV1, TRPV2, and TRPV4 do not participate in the degranulation process triggered by DNP-FcεRI or Compound 48–80.

Fig 3

PMCs were obtained from WT mice (black) and mice deficient (red) for TRPV1 (A), TRPV2 (B), or TRPV4 (C). Bar graphs show the percentage of β-hexosaminidase release. SD-Spontaneous degranulation, Iono- 10μM Ionomycin, 48-80- 50μg/ml Compound 48–80, and 100 ng/ml DNP. ᵻCells were preincubated with αDNP-IgE overnight. Graphs represent the mean ± SEM of at least 4 independent PMCs preparations.