FIG. 1.

Specific lysis of PBAC targets increased as the E:T ratio increased. PBMC from H71 were stimulated in vitro for 5 days with virulent live R. equi and rested for 48 h. Stimulated effectors were then added, at increasing E:T ratios, to autologous and ELA-A mismatched infected and uninfected target cells. Lysis of infected targets was compared to uninfected negative controls. Increasing the number of effectors per infected target increased the percent specific lysis. An asterisk indicates significant increase compared to the corresponding uninfected control at the same E:T ratio.