FIG. 6.
Equivalent lysis of infected targets was mediated by lymphocytes stimulated with either the plasmid-bearing (virulent) or the plasmid-cured (avirulent) strain. PBMC effectors were stimulated with either the PL+ or the PC strain of R. equi. Representative data from horses H71 and H68 at an E:T ratio of 9:1 are presented in the figure. ELA-A-unrestricted lysis of PBAC targets infected with the plasmid-bearing strain (virulent) of R. equi 33701 was equivalent for either stimulated lymphocyte population. The asterisks indicate significant killing compared to the corresponding uninfected control.