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. 2017 Feb 3;12(2):e0171356. doi: 10.1371/journal.pone.0171356

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© 2017 Takeda et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — (A) Morphological changes in parental cell line (BT-474) and its sublines (BT-474-R and BT-474-RL2). (B) MTS assay evaluating cell viability of BT-474, BT-474-R and BT-474-RL2 upon treatment with various concentrations of trastuzumab or lapatinib for 72 hours. Data are shown as means ± standard errors (SE). The assay using trastuzumab was repeated five times, and the assay using lapatinib was repeated three times.