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| Cell line | Characteristics | IC25 (mean ± SE) | IC50 (mean ± SE) |
|---|---|---|---|
| Trastuzumab (μg/mL) | Lapatinib (μM) | ||
| BT-474 | HER2 amplification | 0.114 ± 0.0314 | 0.0178 ± 0.00285 |
| BT-474-R | Trastuzumab-resistant subline | > 1000 | 0.239 ± 0.0443 |
| BT-474-RL2 | Trastuzumab/lapatinib-resistant subline | > 1000 | 3.94 ± 0.225 |
