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. 2017 Feb 3;12(2):e0170301. doi: 10.1371/journal.pone.0170301

Table 2. Inhibitory activity (IC50, μM) against MAO-A and -B and selectivity index for LSD1.

LSD1 MAO-A MAO-B Selectivity index
1 0.0098 17.5 34.2 >1,700
2 0.077 120 480 >1,500
3 0.035 7.3 16.3 >208
7 0.91 0.17 0.35 <0.38
8 5.3 0.42 3.1 <0.58
10 0.064 18.1 23.1 >280
11 0.62 0.26 0.51 <0.82
16 0.062 2.4 1.8 >29
26 0.74 0.30 0.40 <0.54
31 5.8 40.7 87.0 >7
32 0.67 97.5 370 >145