A20 mRNA expression levels in PBMCs from patients with CHB and healthy controls. There was a significant increase in A20 expression in CHB patients compared with healthy controls (A). No significant difference was found between HBV DNA (+) and HBV DNA (−) groups as well as between HBeAg(+) and HBeAg (−) groups (B,C). The expression of A20 was significantly positively correlated with alanine aminotransferase (ALT) (D), aspartate aminotransferase (AST) (E), and serum total bilirubin (TBIL) (F). No significant correlations were found between the A20 mRNA level and albumin (ALB) (G), hepatitis B surface antigen (HBsAg) (H). ALB = albumin, ALT = alanine aminotransferase, AST = aspartate aminotransferase, CHB = chronic hepatitis B, HBeAg = hepatitis B e antigen, HBsAg = hepatitis B surface antigen, HBV = hepatitis B virus, PBMCs = peripheral blood mononuclear cells, TBIL = total bilirubin.