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. 2004 Dec;72(12):7063–7072. doi: 10.1128/IAI.72.12.7063-7072.2004

FIG. 4.

FIG. 4.

Characterization of the deletion junctions of the cytotoxin genes of the ocular serovars. (A) The cytotoxin gene of C. trachomatis serovar H (CtH) has two direct 12-bp repeats separated by 4,956 bp. Recombination between these repeats would result in the sequence of the cytotoxin loci found in serovars A (CtA), Ba (CtBa), and C (CtC), with loss of one of the 12-bp repeats. (B) A large deletion in the cytotoxin region of the genome of serovar B results in the loss of 9,662 bp (in comparison to the D/UW-3/Cx genome sequence), including 10 complete ORFs, the 5′ portion of CT161, and the 3′ portion of CT172. This deletion encompasses the entire cytotoxin locus and the tryptophan synthase regulon.