Figure 2. 17-HDHA and RvD1 reduce induced B cell IgE production from asthma patients not receiving oral corticosteroid treatment.

PBMCs from asthma patients taking only inhaled corticosteroids (A), or those taking oral steroids (B), were treated with SPMs, followed by stimulation with an IgE-inducing cocktail. IgE levels were measured at day 6. Each symbol represents an individual donor and represents means of triplicates. Data were analyzed by repeated-measures 1-way ANOVA with Tukey’s post test, **P ≤ 0.01, ***P ≤ 0.001. PBMC, peripheral blood mononuclear cell; SPM, specialized proresolving mediator.