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. 2016 Nov 14;8(2):114–122. doi: 10.1007/s13238-016-0340-z

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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miR-27b suppresses tumor growth and liver metastasis of gastric cancer cells in vivo. (A) Representative images of primary tumors in the nude mice orthotopically injected with MGC-803/miR-27b or MGC-803/ctrl cells in the leg (left). Quantification of tumors in each group is shown (right). (B) Representative bioluminescence images of mice injected with MGC-803/miR-27b or MGC-803/ctrl cells into spleen to show liver metastases (left). Quantification of liver metastases was analyzed by bioluminescence measurement (right). Scale bars, 100 μm. *P < 0.05, **P < 0.01, ***P < 0.001