Table 1.

Clinical characteristics of females and males with sarcoidosis

	Females (N=174)	Males (N=171)	p value
Mean age at diagnosis in years (SD)	48.3 (14.1)	42.8 (12.6)	< 0.001
Ethnicity			0.15
Caucasian	154 (90%)	147 (90%)
African-American	7 (4%)	11 (7%)
Asian	5 (3%)	1 (1%)
Native American	0 (0%)	2 (1%)
Other	5 (3%)	2 (1%)
Unknown	3	8
Smoking status at diagnosis			0.068
Never	108 (64%)	90 (56%)
Ex-smoker	38 (22%)	33 (20%)
Current smoker	24 (14%)	39 (24%)
Unknown	4	9
Intra-thoracic involvement
Any intra-thoracic involvement	170 (98%)	165 (96%)	0.50
Lung parenchymal disease	78 (46%)	91 (55%)	0.09
Intra-thoracic lymphadenopathy	151 (89%)	142 (86%)	0.45
Pulmonary symptoms	61 (36%)	84 (51%)	0.006
Extra-thoracic involvement
Uveitis	11 (6%)	2 (1%)	0.012
Joint	24 (14%)	18 (11%)	0.35
Nervous system	6 (3%)	6 (3%)	0.78
Cutaneous	43 (25%)	20 (12%)	0.002
Gastrointestinal	0 (0%)	1 (1%)	0.31
Hepatic	10 (6%)	10 (6%)	0.97
Spleen	6 (3%)	7 (4%)	0.75
Cardiac	3 (2%)	1 (1%)	0.32
Bone	1 (1%)	0 (0%)	0.32
Renal	6 (3%)	6 (4%)	0.98
Endocrine gland	1 (1%)	1 (1%)	0.99
Exocrine gland	4 (2%)	3 (2%)	0.72
Laboratory measures
High ACE level	60 of 142 tested patients (42%)	61 of 145 tested patients (42%)	0.98
Hypercalcemia	14 of 150 tested patients (9%)	18 of 145 tested patients (12%)	0.40

SD, standard deviation; ACE, angiotensin converting enzyme