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. 2017 Jan 21;23(3):426–436. doi: 10.3748/wjg.v23.i3.426

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©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Gastric mucosal blood flow before and after oestrogen administration. Gastric mucosal blood flow [laser doppler flow (LDF)] presented as perfusion units (PFU) and mean arterial pressure (MAP) in male (dashed line) and female (solid line) animals. The X-axis shows values at baseline and following oestrogen administration at 0.1 µg/kg•min (E1) as well as 1 µg/kg•min (E2) respectively. Mean blood flow in the gastric mucosa decreased by 31% (68 ± 13 PFU) in males (n = 7) which was significantly different compared to baseline (b).