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Effect of pbp2 expression on vancomycin and oxacillin resistance in S. aureus strain COLVA200
| Strain | IPTG concn (μM) | MIC (μg/ml)
|
|
|---|---|---|---|
| Vancomycin | Oxacillin | ||
| COLVA200 | 1,000 | 800 | |
| COLVA200pPBP2iC | 0 | 1 | 1.0 |
| 25 | 12 | 8.0 | |
| 50 | 90 | 24 | |
| 500 | 400 | >256 | |
| COLVA200Tn551::mecApPBP2iC | 0 | No growth | No growth |
| 25 | <1.5 | 1.5-3 | |
| 50 | 12 | 1.5-3 | |
| 500 | 200 | 1.5-3 | |
| COLVA200RUSA130a | 5 | 6 | |
COLVA200 carrying a Tn551 insert in pbpB (14).
