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. 2017 Feb 3;8:6. doi: 10.1186/s13293-017-0127-9

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — PCA plot of differentially expressed miRNA profiles of 88 rat liver samples. Normalized log2 intensity values for 214 miRNAs that were differentially expressed by age and/or sex in livers of rats of nine ages and both sexes are plotted. Each sphere represents the composite DEM profile from a single animal. Colors represent age groups. Black vertices indicate female animals; males have none