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. 2017 Feb 3;19:22. doi: 10.1186/s13075-017-1227-y

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Effect of blocking α2AP on vascular damage in a bleomycin-induced mouse model of systemic sclerosis. a The skin sections from mice treated with saline, bleomycin plus control IgG, or bleomycin plus α2AP-neutralizing antibodies were stained with antibodies to PECAM1. b The histogram shows quantitative representations of PECAM1 (n = 6). c Blood flow in the skin of mice treated with saline (n = 5), bleomycin plus control IgG (n = 4), or bleomycin plus α2AP-neutralizing antibodies (n = 4). The data represent the mean ± SEM. * P < 0.01. Scale bar, 200 μm