Table 4.

Incidence rates and Cox proportional hazard univariate analysis

Incidence rates per person-year	HIV-Negative	HIV-Positive	Hazard ratio (95% Conf. Interval)	P value
All-cause peritonitisa	0.765	1.855	HR 2.41 (1.69–3.45)	<0.001
Baseline CD4 count
< 200 cells/μL		3.690	HR 4.54 (2.35–8.76)	<0.001
200–350 cells/μL		1.940	HR 2.61 (1.60–4.24)	<0.001
> 350 cells/μL		1.599	HR 2.10 (1.39–3.15)	0.001
Gram-positive peritonitis	0.262	0.675	HR 2.59 (1.46–4.60)	0.001
Gram-negative peritonitis	0.353	0.512	HR 1.40 (0.80–2.44)	0.236
Culture-negative peritonitis	0.150	0.560	HR 3.64 (1.75–7.54)	0.001
Fungal peritonitis	0.028	0.089	HR 3.25 (0.63–16.79)	0.159
Peritonitis relapse	0.078	0.298	HR 3.88 (1.37–10.94)	0.010
Baseline CD4 count
< 200 cells/μL		0.615	HR 10.60 (1.95–57.56)	0.006b
200–350 cells/μL		0.698	HR 8.82 (2.90–26.90)	<0.001b
≥ 350 cells/μL		0.073	HR 0.97 (0.19–5.00)	0.969b
Peritonitis recurrence	0.031	0.137	HR 4.62 (0.92–23.21)	0.063
Peritonitis repeat (same organism)	0.094	0.160	HR 1.81 (0.60–5.42)	0.289
Peritonitis repeat (different organism)	0.156	0.504	HR 3.81 (1.80–8.09)	<0.001
Multiple peritonitisa	0.281	0.802	HR 3.22 (1.82–5.71)	<0.001
Baseline CD4 count
< 200 cells/μL		1.230	HR 8.41 (2.71–26.08)	<0.001b
200–350 cells/μL		0.931	HR 3.90 (1.86–8.18)	<0.001b
> 350 cells/μL		0.690	HR 2.64 (1.38–5.04)	0.003b
Peritonitis hospital admissions	0.815	1.814	HR 2.19 (1.44–3.35)	<0.001
Peritonitis technique failurec	0.195	0.285	HR 1.43 (0.69–2.93)	0.335
All-cause technique failured	0.237	0.338	HR 1.42 (0.73–2.73)	0.299
Peritonitis mortality	0.028	0.071	HR 2.67 (0.49–14.60)	0.258
All-cause mortality	0.181	0.498	HR 2.53 (1.31–4.90)	0.006

HR hazard ratio, CD cluster of differentiation, HIV human immunodeficiency virus

^a Excluding peritonitis relapse episodes; ^b HIV-positive sub-groups compared to the HIV-negative cohort; ^c Peritonitis technique failure - catheter removal due to peritonitis; ^d Technique failure - catheter removal due to catheter malfunction or infection