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. 2017 Feb 3;49:18. doi: 10.1186/s12711-017-0287-4

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Manhattan plots. Manhattan plots of the −log₁₀ p values for association of SNPs with APD, APR and FPD, and the meta-analysis (FDP_meta). The top horizontal line indicates the genome-wide significance level $p_{g e n o m e - w i d e} \leq 0.05$ , and the bottom line indicates the nominal level of significance p ≤ 5 × 10⁻⁵