Table 4.
Genes located in one of the FPDmeta clusters (Table 2) that were significantly differentially-expressed (nominal p value ≤ 0.0001) in the HFP and LFP lines
| ProbeSetIDa | Chrb | Position (Mb)b | FPDmeta cluster | −log10 p | Gene symbol | Gene name | Nfold | Reg |
|---|---|---|---|---|---|---|---|---|
| A_87_P022983 | 3 | 104.30 | 4 | 4.58 | WDR35 | WD repeat domain 35 | 7.80 | Up |
| A_87_P021624 | 3 | 104.33 | 4 | 5.85 | LAPTM4A | lysosomal protein transmembrane 4 alpha | 1.28 | Down |
| A_87_P018137 | 3 | 104.80 | 4 | 5.23 | HS1BP3 | HCLS1 binding protein 3 | 2.53 | Up |
| A_87_P254443 | 3 | 104.84 | 4 | 4.28 | LDAH | lipid droplet associated hydrolase | 1.34 | Up |
| A_87_P176188 | 3 | 105.39 | 4 | 4.16 | LOC769627 | Unknownc | 1.94 | Down |
| A_87_P304288 | 8 | 3.73 | 7 | 5.64 | LOC101751271 | 1-phosphatidylinositol phosphodiesterase-like | 1.88 | Down |
| A_87_P052241 | 8 | 4.03 | 7 | 4.01 | MTA1 | metastasis associated 1 | 1.19 | Down |
| A_87_P079496 | 8 | 25.66 | 8 | 4.58 | GLIS1 | GLIS family zinc finger 1 | 2.02 | Down |
| A_87_P016336 | 8 | 26.00 | 8 | 4.10 | TTC4 | tetratricopeptide repeat domain 4 | 1.37 | Down |
| A_87_P022335 | 8 | 26.00 | 8 | 4.35 | PARS2 | prolyl-tRNA synthetase 2, mitochondrial (putative) | 1.36 | Up |
| A_87_P139413 | 9 | 5.67 | 9 | 4.17 | AQP12 | aquaporin 12 | 1.78 | Up |
| A_87_P012759 | 9 | 5.67 | 9 | 6.92 | AQP12 | aquaporin 12 | 1.67 | Up |
| A_87_P077026 | 9 | 5.68 | 9 | 4.09 | PAK2 | p21(RAC1)activated kinase 2 | 1.96 | Up |
| A_87_P280878 | 9 | 5.69 | 9 | 7.95 | PAK2 | p21(RAC1)activated kinase 2 | 1.81 | Up |
| A_87_P285338 | 9 | 5.76 | 9 | 5.38 | RNF168 | ring finger protein 168 | 1.27 | Down |
| A_87_P017768 | 9 | 5.98 | 9 | 4.12 | PPP1R7 | protein phosphatase 1, regulatory (inhibitor) subunit 7 | 1.21 | Down |
| A_87_P223178 | 9 | 5.98 | 9 | 4.05 | PPP1R7 | protein phosphatase 1, regulatory (inhibitor) subunit 7 | 1.28 | Down |
| A_87_P023784 | 9 | 6.18 | 9 | 6.00 | ETV5 | ets variant 5 | 1.40 | Down |
| A_87_P077621 | 9 | 16.69 | 10 | 4.17 | SLC12A9 | solute carrier family 12 (potassium/chloride transporters), member 9 | 1.51 | Down |
| A_87_P005339 | 9 | 16.78 | 10 | 6.92 | CYP2J6L1 | cytochrome P450 2J6-like 1 | 2.24 | Up |
| A_87_P177293 | 9 | 16.78 | 10 | 4.09 | CYP2J6L1 | cytochrome P450 2J6-like 1 | 1.97 | Up |
| A_87_P077646 | 9 | 16.79 | 10 | 7.95 | CYP2J2L5 | cytochrome P450 2J2-like 5 | 2.25 | Up |
| A_87_P181713 | 19 | 6.94 | 12 | 4.07 | FAM101B | family with sequence similarity 101 member B | 2.17 | Down |
| A_87_P017169 | 19 | 7.26 | 12 | 4.86 | PTRH2 | peptidyl-tRNA hydrolase 2 | 1.16 | Down |
| A_87_P011731 | 19 | 8.05 | 12 | 7.95 | CA4 | carbonic anhydrase IV | 1.74 | Down |
| A_87_P018194 | 24 | 25.84 | 13 | 4.19 | VPS26B | VPS26 retromer complex component B | 3.85 | Up |
The experiment-wide significant genes (Bonferroni corrected, p ≤ 0.05) are written in underline
Italic: Gene symbols
aUnique Agilent ID for the 60mer probe on the Agilent Chicken Gene Expression Microarrays
bChromosomal assignment and position according to genome release galGal2.1
cRecording was discontinued and the probe set could not be assigned to any gene