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. 2017 Feb 3;9:13. doi: 10.1186/s13148-017-0314-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Clinical significance of genes associated with uniquely hypomethylated probes. Kaplan-Meier plots of a CTLA4 showed higher gene expression (high, N = 124) was significantly associated with better disease prognosis than low expression (low, N = 124), while b lower expression of CAMK2B was associated with better prognosis. c Early-stage patients (stages 1 and 2) showed significantly better prognosis with higher expression of CTLA4. Mantel-Cox log-rank P values are presented with each survival analysis