Table 2. Univariate and multivariate logistic regression analyses of clinical characteristics and glycemic measures to poor neurological outcome.
| Poor neurological outcome (mRS ≥ 3 at three months) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Characteristics | Crude OR (95% CI) | p value | Adjusted OR model 1 (95% CI) | p value | Adjusted OR model 2 (95% CI) | p value | Adjusted OR model 3 (95% CI) | p value |
| All patients (n = 484) | ||||||||
| Age | 1.059 (1.040–1.080) | <0.001* | 1.056 (1.032–1.080) | <0.001* | 1.059 (1.034–1.084) | <0.001* | 1.059 (1.034–1.084) | <0.001* |
| Male sex | 0.755 (0.492–1.159) | 0.199 | 0.816 (0.472–1.411) | 0.467 | 0.811 (0.468–1.404) | 0.453 | 0.833 (0.481–1.443) | 0.515 |
| NIHSS at admission | 1.320 (1.246–1.398) | <0.001* | 1.313 (1.237–1.395) | <0.001* | 1.312 (1.235–1.392) | <0.001* | 1.319 (1.241–1.402) | <0.001* |
| Hypertension | 1.159 (0.726–1.851) | 0.535 | ||||||
| Hyperlipidemia | 0.768 (0.482–1.223) | 0.266 | ||||||
| Atrial fibrillation | 2.870 (1.710–4.817) | 0.001* | 1.387 (0.679–2.833) | 0.370 | 1.373 (0.668–2.822) | 0.388 | 1.452 (0.706–2.986) | 0.311 |
| Admission random glucose | 1.002 (0.999–1.004) | 0.158 | 1.002 (0.999–1.005) | 0.228 | ||||
| Fasting glucose | 1.005 (1.002–1.008) | 0.003* | 1.005 (1.003–1.010) | 0.039* | ||||
| HbA1c | 1.032 (0.919–1.158) | 0.600 | 1.160 (0.985–1.366) | 0.076 | ||||
| Nondiabetic patients (n = 212) | ||||||||
| Age | 1.0061 (1.033–1.089) | <0.001* | 1.065 (1.027–1.103) | 0.006* | 1.067 (1.028–1.106) | 0.006* | 1.066 (1.028–1.106) | 0.006* |
| Male sex | 0.632 (0.323–1.233) | 0.178 | 0.722 (0.292–1.782) | 0.479 | 0.711 (0.288–1.758) | 0.461 | 0.685 (0.275–1.702) | 0.415 |
| NIHSS at admission | 1.347 (1.231–1.473) | <0.001* | 1.355 (1.229–1.493) | <0.001* | 1.345 (1.220–1.482) | <0.001* | 1.359 (1.232–1.500) | <0.001* |
| Hypertension | 1.013 (0.521–1.968) | 0.969 | ||||||
| Hyperlipidemia | 0.659 (0.311–1.394) | 0.275 | ||||||
| Atrial fibrillation | 2.787 (1.313–5.916) | 0.008* | 1.424 (0.498–4.076) | 0.510 | 1.334 (0.471–3.792) | 0.586 | 1.396 (0.494–5.859) | 0.529 |
| Admission random glucose | 1.003 (0.995–1.012) | 0.453 | 0.999 (0.987–1.012) | 0.886 | ||||
| Fasting glucose | 1.025 (1.009–1.041) | 0.002* | 1.011 (0.992–1.031) | 0.272 | ||||
| HbA1c | 1.124 (0.493–2.564) | 0.782 | 1.700 (0.494–5.859) | 0.400 | ||||
| Diabetic patients (n = 272) | ||||||||
| Age | 1.057 (1.030–1.086) | <0.001* | 1.049 (1.017–1.082) | 0.002* | 1.053 (1.021–1.087) | 0.001* | 1.055 (1.021–1.089) | 0.001* |
| Male sex | 0.867 (0.497–1.514) | 0.616 | 0.892 (0.445–1.788) | 0.747 | 0.873 (0.434–1.755) | 0.703 | 0.914 (0.455–1.837) | 0.801 |
| NIHSS at admission | 1.304 (1.209–1.407) | <0.001* | 1.291 (1.194–1.395) | <0.001* | 1.286 (1.190–1.389) | <0.001* | 1.295 (1.197–1.400) | <0.001* |
| Hypertension | 1.257 (0.632–2.500) | 0.515 | ||||||
| Hyperlipidemia | 0.843 (0.464–1.531) | 0.575 | ||||||
| Atrial fibrillation | 3.089 (1.500–6.361) | 0.002* | 1.436 (0.527–3.915) | 0.480 | 1.361 (0.493–3.761) | 0.552 | 1.496 (0.545–4.111) | 0.435 |
| Admission random glucose | 1.001 (0.999–1.004) | 0.319 | 1.002 (0.998–1.006) | 0.319 | ||||
| Fasting glucose | 1.004 (1.001–1.008) | 0.003* | 1.005 (0.999–1.010) | 0.110 | ||||
| HbA1c | 1.000 (0.863–1.161) | 0.992 | 1.163 (0.945–1.430) | 0.154 | ||||
Notes.
*
p < 0.05.
- OR
- odds ratio
Model 1 included age, sex, NIHSS at admission, atrial fibrillation, and admission random glucose.
Model 2 included age, sex, NIHSS at admission, atrial fibrillation, and fasting glucose.
Model 3 included age, sex, NIHSS at admission, atrial fibrillation, and HbA1c.