TABLE 1.
PI-1 (nM)/IFN-α (U/ml) ratio | CI values at:
|
||
---|---|---|---|
ED50 | ED75 | ED90 | |
2:1 | 0.49 | 0.65 | 0.91 |
6:1 | 0.86 | 0.79 | 0.74 |
18:1 | 0.86 | 0.78 | 0.73 |
ED50, ED75, and ED90 are the EDs of the compounds required to achieve 50, 75, and 90% inhibition, respectively. The CI values at various percentages of inhibition were calculated with the CalcuSyn program, as described in Materials and Methods.