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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Exp Dermatol. 2016 Dec 20;26(8):736–738. doi: 10.1111/exd.13150

Figure 2.

Figure 2

Skin inflammation and epidermal barrier defects in the Mpzl3−/− mice. (a–d) Increased T-helper cell (CD4 positive) (a, b) and macrophage (CD11-b positive) (c, d) infiltrates in the dermis of Mpzl3−/− eyelids. (e–j) Gross phenotype (e–g) and hematoxylin and eosin staining of skin sections (h–j) showing skin inflammation and alopecia (arrows) in Mpzl3−/−|Rag2−/− mice (g, j) similar to that of Mpzl3−/− mice (f, i), compared with wild type mice (e, h). (k, l) Increased toluidine blue dye permeability +/− in E17.0 Mpzl3−/− embryos.