Table 1.
| a. Recipient Characteristics | |||||
|---|---|---|---|---|---|
| Characteristic | ALL (N=560) |
No UNOS-DGF (N=345) |
UNOS-DGF (N=215) |
P- value * |
|
| Age, years | 55 [46, 63] | 54 [45, 63] | 55 [46, 64] | 0.287 | |
| Sex, male | 353 (63%) | 207 (60%) | 146 (68%) | 0.059 | |
| Black race | 262 (47%) | 138 (40%) | 124 (58%) | <0.001 | |
| Body mass index, kg/m2 | 27 [24, 31.1] | 27 [24, 30] | 29 [25, 33] | <0.001 | |
| Cause of ESRD | Diabetes | 143 (26%) | 88 (26%) | 55 (26%) | 0.338 |
| Hypertension | 143 (26%) | 84 (24%) | 59 (27%) | ||
| Glomerulonephritis | 77 (14%) | 52 (15%) | 25 (12%) | ||
| CAKUT | 42 (8%) | 21 (6%) | 21 (10%) | ||
| Failed transplant | 85 (15%) | 58 (17%) | 27 (13%) | ||
| Other | 70 (13%) | 42 (12%) | 28 (13%) | ||
| Dialysis type before transplant |
Hemodialysis | 446 (80%) | 248 (73%) | 198 (92%) | <0.001 |
| Peritoneal | 72 (13%) | 57 (17%) | 15 (7%) | ||
| Pre-emptive | 38 (7%) | 36 (11%) | 2 (1%) | ||
| Dialysis vintage, months | 49 [19.5, 71] | 40.5 [10, 65.5] | 59 [36, 76.5] | <0.001 | |
| Hepatitis C seropositive | 38 (7%) | 25 (7%) | 13 (6%) | 0.451 | |
| PRA, % | 0% | 367 (66%) | 224 (65%) | 143 (67%) | 0.278 |
| 1–20% | 37 (7%) | 20 (6%) | 17 (8%) | ||
| 21–80% | 75 (13%) | 44 (13%) | 31 (14%) | ||
| >80% | 81 (14%) | 57 (17%) | 24 (11%) | ||
| b. Allograft (Donor) Characteristics | |||||
|---|---|---|---|---|---|
| Characteristic | ALL (N=560) |
No UNOS-DGF (N=345) |
UNOS-DGF (N=215) |
P- value* |
|
| Age, years | 43 [27, 53] | 38 [25, 51] | 47 [31, 56] | <0.001 | |
| Sex, male | 347 (62%) | 217 (63%) | 130 (60%) | 0.564 | |
| Black race | 96 (17%) | 62 (18%) | 34 (16%) | 0.510 | |
| Kidney Donor Risk Index | 1.22 [0.97, 1.52] | 1.11 [0.92, 1.47] | 1.36 [1.12, 1.62] | <0.001 | |
| Kidney Donor Profile Index, % | 49 [26, 70] | 40 [21, 67] | 60 [40, 76] | <0.001 | |
| Cause of death | Head trauma | 156 (28%) | 113 (33%) | 43 (20%) | 0.003 |
| Anoxia | 188 (34%) | 113 (33%) | 75 (35%) | ||
| Stroke | 208 (37%) | 116 (34%) | 92 (43%) | ||
| Other | 7 (1%) | 2 (1%) | 5 (2%) | ||
| History of diabetes | 58 (10%) | 31 (9%) | 27 (13%) | 0.177 | |
| History of hypertension | 166 (30%) | 88 (26%) | 78 (36%) | 0.007 | |
| Hepatitis C seropositive | 16 (3%) | 11 (3%) | 5 (2%) | 0.551 | |
| DCD | 100 (18%) | 46 (13%) | 54 (25%) | <0.001 | |
| Terminal SCr, mg/dl | 1 [0.7, 1.4] | 0.9 [0.7, 1.2] | 1.1 [0.7, 1.6] | 0.001 | |
| Cold ischemia time, hours | 16.2 [12.5, 22] | 16 [12, 21.5] | 17 [13, 23.4] | .064 | |
| Number of HLA mismatches |
0 | 20 (4%) | 15 (4%) | 5 (2%) | 0.844 |
| 1 | 11 (2%) | 7 (2%) | 4 (2%) | ||
| 2 | 13 (2%) | 8 (2%) | 5 (2%) | ||
| 3 | 75 (13%) | 48 (14%) | 27 (13%) | ||
| 4 | 140 (25%) | 89 (26%) | 51 (24%) | ||
| 5 | 186 (33%) | 109 (32%) | 77 (36%) | ||
| 6 | 111 (20%) | 67 (20%) | 44 (21%) | ||
Values are median [interquartile range] or n (%). DGF, delayed graft function; ESRD, end-stage renal disease; CAKUT, congenital anomalies of the kidney and urinary tract; PRA, panel reactive antibody.
*
Wilcoxon rank sum test for continuous variables and Pearson’s chi-square test for categorical variables.
Values are median [interquartile range] or n (%). DGF, delayed graft function; DCD, donation after circulatory determination of death. HLA, human leukocyte antigen.