Table 1.
Anesthetic combinations of dexmedetomidine and tiletamine-zolazepam with or without butorphanol. BALB/c female mice were assigned with the intent for six mice in each group, but, due to the high mortality associated with the use of tiletamine-zolazepam above 50 mg/kg, groups were reduced. Dexmedetomidine and tiletamine-zolazepam were given IP and butorphanol was given SC.
| Dexmedetomidine (mg/kg) | Dexmedetomidine (mg/kg) | ||||
|---|---|---|---|---|---|
| Tiletamine-zolazepam (mg/kg) | Tiletamine-zolazepam (mg/kg) | ||||
| (n) | Butorphanol (3 mg/kg) | ||||
| (n) | |||||
| 0.4 | 0.4 | 0.4 | 0.2 | 0.2 | 0.2 |
| 20 | 40 | 60 | 10 | 20 | 40 |
| (n = 6) | (n = 6) | (n = 3) | (n = 6) | (n = 6) | (n = 6) |
|
| |||||
| 0.6 | 0.6 | 0.6 | 0.4 | 0.4 | 0.4 |
| 20 | 40 | 60 | 10 | 20 | 40 |
| (n = 6) | (n = 6) | (n = 3) | (n = 6) | (n = 6) | (n = 6) |
|
| |||||
| 0.8 | 0.8 | 0.8 | 0.6 | 0.6 | 0.6 |
| 20 | 40 | 60 | 10 | 20 | 40 |
| (n = 6) | (n = 5) | (n = 2) | (n = 6) | (n = 6) | (n = 6) |