TABLE 2.

Percent inhibition of A. castellanii growth by the drugs tested at concentrations ≤10 μg/ml^a

Drug	Concn range (μg/ml)	Concn (μg/ml)	% Inhibition ± SE
			Day 2	Day 3	Day 6
Acyclovir	100-12.50		NDb	ND	ND
Amphotericin B	100-0.05	3.125	86.67 ± 2.2	61.42 ± 3.6	58.29 ± 4.2
Amphotericin B		6.25	100	74.45 ± 4.7	62.80 ± 3.8
AZT	10-0.02	2.50	43.40 ± 1.8	22.52 ± 3.2	24.25 ± 2.5
AZT		5.00	66.13 ± 5.2	33.88 ± 1.9	28.55 ± 2.8
AZT		10.00	100	59.49 ± 1.3	46.78 ± 3.6
Chlorpromazine	100-0.05	1.56	100	87.99 ± 4.1	70.41 ± 5.3
Chlorpromazine		3.125	100	92.12 ± 3.3	70.59 ± 3.7
Chlorpromazine		6.25	100	100	82.83 ± 2.6
Erythromycin	100-0.05	6.25	70.80 ± 1.4	46.82 ± 4.0	49.50 ± 3.4
Fusidic acid	125-0.06	7.812	0	0	0
Ornidazole	100-0.05	3.125	64.50 ± 4.9	54.33 ± 4.6	59.06 ± 3.5
Ornidazole		6.125	67.93 ± 3.7	57.93 ± 4.2	61.13 ± 5.0
Pefloxacin	250-0.12		ND	ND	ND
Polymyxin B	100-0.05	6.25	70.83 ± 3.4	72.19 ± 4.1	56.34 ± 4.7
Rokitamycin	300-0.15	2.34	94.73 ± 1.2	64.30 ± 3.6	69.94 ± 3.2
Rokitamycin		4.68	100	75.08 ± 2.8	73.54 ± 2.8
Rokitamycin		9.37	100	89.70 ± 4.3	80.15 ± 3.6
Suramin	100-0.05	6.25	0	0	0

^aInhibition of growth in PYG medium at 37°C in a 5% CO₂ atmosphere was scored on days 2, 3, and 6. Values are the means ± standard errors (SEs) of at least three different experiments.

^bND, not determined.