Table II.
| A, Myocardial infarction (MI) rates
| |||||
|---|---|---|---|---|---|
| None, % | AP only, % | Statin only, % | Both | Pa | |
| Overall | 2.4 | 2.6 | 2.8 | 3.7 | .003b |
| Cardiac risk | |||||
| Low | 1.4 | 1.5 | 1.9 | 2.1 | .3 |
| Medium | 3.1 | 2.5 | 3.0 | 4.6 | .054 |
| High | 5.0 | 6.0 | 5.3 | 7.1 | .48 |
| B, Myocardial infarction (MI) or death rates
| |||||
|---|---|---|---|---|---|
| None, % | AP only, % | Statin only, % | Both, % | Pa | |
| Overall | 3 | 4 | 4 | 5 | .06 |
| Cardiac risk | |||||
| Low | 1.9 | 1.8 | 2.2 | 2.4 | .41 |
| Medium | 4.6 | 4.2 | 4.4 | 5.3 | .62 |
| High | 7.0 | 8.1 | 9.2 | 8.9 | .78 |
AP, Antiplatelet agent (aspirin or P2Y12a antagonist).
a
χ2 comparison.
b
P value listed for overall comparison across groups. After correction for multiple comparisons, MI rate for patients taking both medications was significantly higher than for patients taking neither medication (P = .008) and AP only (P = .008) but not compared with those taking statin only (P = .06).