Table 1.
Patient Demographic and Operative Characteristics in the Study Cohort with p Values from the Study Cohort and Group Frequency Matched Cohort
| Patient and operative characteristics | 0 U (n = 1,532) | 1 to 2 U (n = 248) | 3+ U (n = 100) | p Value study cohort | p Value matched cohort |
|---|---|---|---|---|---|
| Patient characteristics | |||||
| Male sex, n (%) | 1,048 (68.4) | 152 (61.3) | 67 (67) | 0.085 | 0.023 |
| White race, n (%) | 1,508 (99.3) | 245 (100) | 98 (98) | 0.123 | 0.223 |
| Age, y, mean ± SD | 69.5 ± 11.4 | 73.9 ± 10.5 | 75 ± 10.8 | <0.0001 | 0.64 |
| Smoking (past/current), n (%) | 1,257 (82.2) | 186 (75) | 77 (77.8) | <0.0001 | 0.027 |
| Hypertension, n (%) | 1,350 (88.1) | 237 (96) | 94 (94) | 0.0003 | 0.112 |
| COPD, n (%) | 448 (29.2) | 59 (23.8) | 34 (34) | 0.105 | 0.209 |
| Diabetes, n (%) | 892 (58.2) | 167 (67.3) | 76 (76) | 0.0001 | 0.818 |
| Coronary disease, n (%) | 605 (39.5) | 120 (48.4) | 49 (49) | 0.008 | 0.879 |
| Congestive heart failure, n (%) | 289 (18.9) | 71 (28.6) | 38 (38) | <0.0001 | 0.012 |
| End-stage renal failure, n (%) | 140 (9.1) | 29 (11.7) | 13 (13) | 0.232 | 0.596 |
| Creatinine, mg/dL, mean ± SD | 1.6 ± 1.6 | 1.9 ± 1.7 | 2 ± 2 | 0.0007 | 0.181 |
| Hemoglobin, g/dL, mean ± SD | 12.7 ± 2.1 | 10.7 ± 2 | 10.8 ± 2 | <0.0001 | <0.0001 |
| Indication, n (%) | |||||
| Rest pain | 546 (35.6) | 61 (24.6) | 23 (23) | 0.0002 | 0.251 |
| Tissue loss | 986 (64.4) | 187 (75.4) | 77 (77) | ||
| Previous bypass | 477 (31.1) | 82 (33.1) | 42 (42) | 0.072 | 0.112 |
| Operative characteristics | |||||
| Urgency, n (%) | |||||
| Elective | 1,201 (78.4) | 175 (70.6) | 69 (69) | <0.004 | 0.519 |
| Urgent | 331 (21.6) | 73 (29.4) | 31 (31) | ||
| Estimated blood loss, mL, mean ± SD | 220.7 ± 238.7 | 372.9 ± 309.1 | 724 ± 807.9 | <0.0001 | <0.0001 |
| Graft origin, n (%) | |||||
| Common femoral | 1,000 (65.4) | 172 (69.4) | 63 (63) | 0.636 | 0.951 |
| Profunda/superficial femoral | 359 (23.5) | 53 (21.4) | 23 (23) | ||
| AK pop/BK pop/tibial | 170 (11.1) | 23 (9.3) | 14 (14) | ||
| Graft recipient, n (%) | |||||
| AK pop/BK pop | 777 (50.7) | 107 (43.7) | 38 (38) | 0.037 | 0.621 |
| TP trunk/AT/PT/peroneal | 552 (36) | 105 (42.3) | 46 (46) | ||
| DP, PT ankle/tarsal/plantar | 203 (13.3) | 36 (14.5) | 16 (16) | ||
| Conduit type, n (%) | |||||
| Greater saphenous | 1,045 (68.2) | 170 (68.5) | 63 (63) | 0.513 | 0.858 |
| Arm vein | 133 (8.7) | 27 (10.9) | 12 (12) | ||
| Prosthetic | 383 (25) | 61 (24.6) | 28 (28) | ||
| Anesthesia, n (%) | |||||
| Spinal | 236 (15.4) | 45 (18.1) | 8 (8) | 0.044 | 0.023 |
| Epidural | 127 (8.3) | 15 (6) | 4 (4) | ||
| General | 1,169 (76.3) | 188 (75.8) | 88 (88) | ||
| Preoperative medications, n (%) | |||||
| Aspirin | 1,069 (69.8) | 178 (71.8) | 76 (76) | 0.366 | 0.754 |
| Clopidogrel | 152 (9.9) | 37 (14.9) | 18 (18) | 0.005 | 0.03 |
| Statin | 926 (60.5) | 146 (58.9) | 74 (74) | 0.021 | 0.036 |
AK pop, above-knee popliteal; AT, anterior tibial; BK pop, below-knee popliteal; DP, dorsalis pedis; PT, posterior tibial; TP, tibioperoneal.