Table V.
Multivariable predictors of all-cause mortality and aneurysm-related mortality (ARM) in 489 patients with preoperative anatomic data at the initial endovascular aortic aneurysm repair (EVAR) procedure
| Predictors | Adverse eventsa (n = 48)
|
All-cause mortality (n = 104)
|
ARMa (n = 10)
|
|||
|---|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | |
| IFU adherence | 1.0 (0.7–1.5) | .91 | ||||
| Female | 1.2 (0.6–2.3) | .60 | ||||
| Age ≥80 years | 2.2 (1.2–4.0) | <.01 | 1.9 (1.2–2.8) | <.01 | 6.7 (1.7–25.9) | <.01 |
| Preoperative AAA sac size ≥5.5 cm | 2.4 (1.4–3.8) | <.001 | ||||
| Treated with statin | 1.2 (0.8–2.1) | .39 | ||||
| Coronary artery disease | 0.8 (0.5–1.3) | .38 | ||||
| Diabetes | 1.6 (1.04–2.6) | .03 | ||||
| Hyperlipidemia | 0.7 (0.4–1.2) | .15 | ||||
| Hypertension | 1.4 (0.8–2.6) | .27 | ||||
| Peripheral vascular disease | 1.6 (1.04–2.6) | .04 | ||||
| Preoperative embolization | 1.4 (0.7–3.0) | .33 | ||||
| Smoking | ||||||
| Neverb | 1.0 | 1.0 | 1.0 | |||
| Current | 0.7 (0.3–1.2) | .18 | ||||
| Former | 1.1 (0.6–1.8) | .85 | ||||
| Operative adjunctive maneuver | 4.2 (1.4–12.2) | <.01 | 0.8 (0.3–2.4) | .72 | ||
| Bifurcated graft | 1.3 (0.7–2.3) | .36 | ||||
| Any intraoperative endoleak | 0.1 (0.01–0.6) | .02 | 1.0 (0.5–1.8) | .88 | ||
| Any postoperative type I or III endoleak | 8.8 (4.5–17.2) | <.001 | 1.3 (0.6–3.0) | .52 | 8.6 (2.2–33.6) | <.01 |
| Any reinterventionc | N/A | 0.9 (0.5–1.5) | .62 | |||
AAA, Abdominal aortic aneurysm; CI, confidence interval; HR, hazard ratio; IFU, instructions for use; N/A, not applicable.
Because of the small number of patients with adverse events and ARM, a “stepwise” method was used in the multivariable regression model; therefore, the results included in the table are limited to predictors with effects meeting the significance level of .05 to enter and to remain in the model.
Referent group.
Used in the multivariable regression models for all-cause mortality and ARM only.