Table 2.
Distribution of virulence-associated traits among ST131 and non-ST131 E. coli fecal isolates from long-term care facility residents colonized with fluoroquinolone-resistant Escherichia coli.
| Trait | Prevalence of trait, no. (%) | P valuea,b | ||
|---|---|---|---|---|
| ST131 (n = 29) |
Non-ST131 (n = 8) |
|||
| Adhesins | papAHc | 0 (0) | 1 (13) | 0.22 |
| iha | 21 (72) | 3 (38) | 0.10 | |
| fimH | 29 (100) | 6 (75) | 0.04 | |
| Toxins | sat | 23 (79) | 3 (38) | 0.04 |
| vat | 0 (0) | 5 (63) | < 0.001 | |
| hlyFd | 0 (0) | 1 (13) | 0.22 | |
| Siderophores | iroN | 0 (0) | 1 (13) | 0.22 |
| fyuA | 29 (100) | 7 (88) | 0.22 | |
| Miscellaneous | usp | 27 (93) | 4 (50) | 0.01 |
| traT | 27 (93) | 5 (63) | 0.06 | |
| cvaC | 9 (0) | 1 (13) | 0.22 | |
| K1 | 29 (100) | 1 (13) | 0.22 | |
| ompT | 29 (100) | 5 (63) | 0.007 | |
| iss | 0 (0.0) | 1 (13) | 0.22 | |
| H7 fliC | 0 (0) | 2 (25) | 0.04 | |
| malX | 49 (100) | 6 (75) | 0.04 | |
| clbB/N | 0 (0) | 1 (13) | 0.22 | |
Only traits that yielded a P value < 0.30 (by Fisher exact test) are shown. papAH (P fimbria structural subunit), iha (adhesin-siderophore), fimH (type 1 fimbria adhesin), sat (secreted autotransporter toxin), vat (vacuolating toxin), hlyF (hemolysin F), iroN (catecholate siderophore receptor), fyuA (yersiniabactin receptor), usp (uropathogenic-specific protein), traT (serum resistance outer membrane protein), cvaC (colicin V precursor), K1 (group 2 capsule variant), ompT (outer membrane protease), iss (increased serum survival protein), H7 (flagellar variant), malX (pathogenicity island marker), and clbB/N (colibactin synthesis system).
The presence of the following traits were evaluated but not detected in any isolate: papG allele I (P adhesin variant), papG allele III (P adhesin variant), sfa/focDE (S and F1C fimbriae), sfaS (S fimbriae), focG (F1C fimbriae), afa/draBC (Dr-binding adhesins), afaE8 (variant afimbrial adhesin), bmaE (M-agglutinin subunit), gafD (G fimbriae), F17 (fimbrial adhesin), clpG (CS31A surface antigen), hlyD (hemolysin D), cnf1 (cytotoxic-necrotizing factor 1), cdtB (cytolethal distending toxin), tsh (temperature sensitive hemagglutinin), ireA (siderophore receptor), iutA (aerobactin receptor), kpsM II (group 2 capsule), kpsM III (group 3 capsule), K5 (group 2 capsule variant), K15 (group 2 capsule variant), K2/K100 (group 2 capsule variants), rfc (O4 antigen polymerase), and ibeA (invasion of brain endothelium).
papC (P fimbria assembly), papEG (P fimbria tip pilins), papG allele II (P adhesin variant), and hra (heat-resistant agglutinin) demonstrated similar results to those for papAH.
pic (protein associated with intestinal colonization) and astA (enteroaggregative E. coli toxin) demonstrated similar results to those for hlyF.