Table 4.
North American - European divergences across oceans in gluten-sensitive enteropathy
| Target | Screening | PS Tests1 | HLA-DQ | EMA | AGA | |
| ESPGHAN | Paediatric | Anti-tTG-IgA and IgA2 | Anti-tTG-IgG/anti-DPG-IgG3 | Yes, if | Yes, in confirming PS tests | No |
| ↑EMA/anti-tTG | ||||||
| ACG | Paediatric/adult | Anti-tTG-IgA | Anti-tTG-IgG/anti-DPG-IgG3 | Yes, if biopsy/serology disagreement | NS | No |
| WGO | NS | Anti-tTG-IgA/anti-DPG IgG | NS | Yes, if biopsy/serology disagreement | Yes, in confirming PS tests | No |
1
Postscreening tests;
2
Total serum IgA;
3
Anti-DPG: Anti-deamidated gliadin peptide. ESPGHA: European Society of Pediatric Gastroenterology, Hepatology and Nutrition; ACG: American College of Gastroenterology; WGO: World Gastroenterology Organization; NS: Not specified.