Table 1.
First-line eradication therapy |
Second-line eradication therapy |
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VPZ group | PPI group | EPZ group | RPZ group | LPZ group | VPZ group | PPI group | EPZ group | RPZ group | LPZ group | |
n = 546 | n = 807 | n = 507 | n = 89 | n = 211 | n = 76 | n = 185 | n = 104 | n = 24 | n = 57 | |
Age, mean ± SD, yr | 57.4 ± 11.8 | 56.7 ± 12.8 | 56.9 ± 11.6 | 60.7 ± 11.2 | 56.1 ± 12.1 | 56.9 ± 12.8 | 56.0 ± 12.6 | 57.5 ± 12.5 | 58.2 ± 12.2 | 58.1 ± 12.3 |
Sex, n (%) | ||||||||||
Male | 225 (41.2) | 318 (39.4) | 193 (38.1) | 35 (39.3) | 90 (42.7) | 30 (39.5) | 71 (38.4) | 39 (37.5) | 9 (39.3) | 23 (40.4) |
Female | 321 (58.8) | 489 (60.6) | 314 (61.9) | 54 (60.7) | 121 (57.3) | 46 (60.5) | 114 (61.6) | 65 (62.5) | 15 (60.7) | 34 (59.6) |
Indication | ||||||||||
GU(s) | 32 | 33 | 18 | 4 | 11 | 3 | 7 | 6 | 0 | 1 |
DU(s) | 37 | 68 | 36 | 8 | 24 | 5 | 13 | 5 | 2 | 6 |
GDU(s) | 4 | 4 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
MALT lymphoma | 0 | 2 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 1 |
Post ESD | 1 | 3 | 2 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
Atrophic gastritis | 472 | 697 | 449 | 76 | 172 | 66 | 164 | 93 | 22 | 49 |
GU/GUs: Gastric ulcer and/or ulcer scar; DU/DUs: Duodenal ulcer and/or ulcer scar; GDU/GDUs: Gastroduodenal ulcer and/or ulcer scar; MALT: Mucosa-associated lymphoid tissue; ESD: Endoscopic submucosal dissection; VPZ: Vonoprazan; PPI: Proton pump inhibitor; EPZ: Esomeprazole; RPZ: Rabeprazole; LPZ: Lansoprazole.