Table 2.
Level of relevance | General characteristics | Disability | Motor symptoms related with treatment | Motor symptoms related with the disease | Nonmotor symptoms related with the disease | Neuropsychiatric and cognitive symptoms |
---|---|---|---|---|---|---|
Definitive symptoms | Requiring help to perform daily living activities | Presence of motor fluctuations with an off time > 25%, with limitation to perform basic activities, without requiring help | Severe dysphagia Recurrent falls |
Dementia | ||
| ||||||
Probable∗symptoms | Evolution time (around 10 years) | Limitation to perform basic activities, although not requiring help | Functional disability due to dyskinesias with an on time > 25% | Moderate dysphagia Freezing of gait Moderate-severe dysarthria |
Hallucinations without preserved insight | |
| ||||||
Possible∗∗ symptoms | Postural and equilibrium disorders | Symptomatic dysautonomia, including orthostatic symptomatic hypotension, excessive daytime somnolence |
Moderate-severe apathy Chronic presence of hallucinations with preserved insight Psychotic symptoms Mild cognitive impairment |
∗The association of two probable symptoms of different areas (general characteristics, disability, motor symptoms related to treatment, etc.) makes them a definite symptom.
∗∗The association of one possible motor or nonmotor symptom related with the disease areas with one possible symptom of the neuropsychiatric and cognitive area makes them a probable symptom.