Table 1.

Intracerebral pathogenicity index (ICPI) scores and MDT values for parental rLaSota and rSG10 and their envelope-associated protein gene chimeras.

Virus	ICPI scorea	MDT (h)b
rLaSota	0.00	>120
rLaSGFHN	1.49ˆ*	79ˆ*
rSG10	1.86	57
rSGLaFHN	0.86ˆ*	>120ˆ*

^aPathotype definitions by ICPI: virulent strains, 1.50–2.00; moderately virulent strains, 0.70–1.50; avirulent strains, 0.00–0.70. ^bPathotype definitions by MDT: virulent strains, <60 h; moderately virulent strains, 60–90 h; avirulent strains, >90 h. Asterisks indicate the statistical significance of the ICPI score and MDT of a chimeric virus compared to the parental virus of that group. P-values were calculated based on a two-tailed, unpaired t-test (95% confidence levels). ^∗p = 0.01–0.05, significant.