TABLE 6.

Distribution of fu AUC_0-24/MIC ratios stratified by clinical and bacteriologic responses

fu AUC0-24/MIC ratio	Clinical response				Bacteriologic response
	No. of patients	Cure	Failure	% Cure	No. of patients	Eradicated	Persisted	% Eradicated
S. pneumoniae
0-200	1	1	0	100	1	1	0	100
201-400	36	35	1	97.2	35	33	2	94.3
401-600	21	19	2	90.5	20	18	2	90.0
601-800	21	18	3	85.7	19	17	2	89.5
801-1,000	11	10	1	90.9	11	10	1	90.9
>1,000	6	4	2	66.7	5	3	2	60.0
Total	96	87	9	90.6	91	82	9	90.1
H. influenzae, H. parainfluenzae, M. catarrhalis
0-200	20	19	1	95.0	16	13	3	81.2
201-400	26	25	1	96.2	26	24	2	92.3
401-600	22	21	1	95.5	20	20	0	100
601-800	23	22	1	95.7	23	21	2	91.3
801-1,000	13	11	2	84.6	13	12	1	92.3
>1,000	112	103	9	92.0	109	100	9	91.7
Total	216	201	15	93.1	207	190	17	91.8