Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jan 20;6(1):e126. doi: 10.1038/cti.2016.87

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

The relationships of EBV genome load and anti-EBV antibody titres with the frequency of EBV-specific CD8⁺ T cells in MS. (a) EBV DNA copy number in the PBMC in healthy EBV-seropositive subjects (healthy controls (HC)) and patients with MS (MS) (medians with interquartile ranges indicated by black horizontal lines), with P-value determined by the Mann–Whitney test. (b) Relationship between the EBV genome load and the LCL-specific CD8⁺ T-cell frequency in MS patients. (c) Titres of anti-EBNA1 IgG and anti-VCA IgG in the sera of healthy EBV-seropositive subjects (HC) and patients with MS (MS) (medians with interquartile ranges indicated by black horizontal lines), with bracketed P-values determined by the Mann–Whitney test. (d) Relationship between the anti-EBNA1 IgG titre and the LCL-specific CD8⁺ EMRA T-cell frequency in the PBMC in MS patients. (e) Relationship between the anti-VCA IgG titre and the LCL-specific CD8⁺ EMRA T-cell frequency in the PBMC in MS patients (f) Relationship between the anti-VCA IgG titre and the EBV genome load in HC and patients with MS (MS). (g) Relationship between the anti-VCA IgG titre and the EBV genome load in the combined groups of HC and patients with MS. (h) Relationship between the anti-EBNA1 IgG titre and the EBV genome load in HC and patients with MS.