Table 1. General characteristics of healthy subjects and patients with MS.
| HC (n=56) | All MS (n=95) | CIS (n=8) | RRMS (n=33) | SPMS (n=31) | PPMS (n=23) | |
|---|---|---|---|---|---|---|
| Age (years) | 44.0 (32.3–52.8) | 43.0 (37.0–54.0) | 38.5 (26.3–42.5) | 39.0 (33.0–47.0) | 48.0 (41.0–56.0) | 51.0 (39.0–56.0) |
| Sex (% female) | 83.9 | 72.6 | 50.0 | 84.8 | 74.2 | 60.8 |
| Age of onset of MS (years) | 34.0 (26.0–40.0) | 36.3 (25.0–41.9) | 32.0 (27.0–37.8) | 28.0 (24.0–39.0) | 37.0 (33.0–48.0) | |
| Duration of MS (years) | 8.0 (3.0–17.0) | 0.5 (0.1–4.1) | 3.0 (1.0–10.0) | 16.0 (10.0–25.0) | 9.0 (5.0–18.0) | |
| EDSS score | 5.0 (2.5–6.5) | 0.0 (0.0–2.5) | 2.0 (1.0–3.5) | 6.5 (5.5–8.0) | 6.5 (5.5–8.0) | |
| MSSS | 6.6 (3.7–8.8) | 0.7 (0.4–6.6) | 4.6 (2.4–6.6) | 7.5 (5.6–9.1) | 8.3 (6.6–9.7) |
Abbreviations: All MS, total group of MS patients; CIS, clinically isolated syndrome; EDSS, Expanded Disability Status Scale; HC, healthy control subjects; MS, multiple sclerosis; MSSS, MS Severity Score; SPMS, secondary progressive MS; PPMS, primary progressive MS; RRMS, relapsing–remitting MS.
All values except for sex presented as medians (interquartile ranges).