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. 2017 Feb 6;11:48. doi: 10.3389/fnhum.2017.00048

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Copyright © 2017 James, Baldinger-Melich, Philippe, Kranz, Vanicek, Hahn, Gryglewski, Hienert, Spies, Traub-Weidinger, Mitterhauser, Wadsak, Hacker, Kasper and Lanzenberger.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Treatment-induced changes in the relation of SERT availability in depressive patients after administration of SSRI in two different treatment conditions (PET 2, PET 3) compared to baseline (PET 1). The lower triangle denotes significant increases in relations after a single oral SSRI dose in depressive patients (p < 0.05; uncorrected). The upper triangle shows significant increases after 3 weeks of treatment (p < 0.05; uncorrected). Framed squares indicate changes which remain significant after FDR correction for multiple comparison at p < 0.05. ACC, anterior cingulate cortex; the color table indicates changes in correlation coefficients (Δρ).