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Induction of basophil degranulation with sera obtained from different groups of mice on days 164, 172, and 179. The time point of boosting (B) is indicated by an arrow. RBL cells were loaded with pooled serum IgE from the respective groups of mice (groups A–F) and challenged with a peptide–OVA conjugate. The mean β-hexosaminidase releases ± SD (y-axes) are shown for each group of mice on different days (x-axes) as percentages of total releases.
