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Deoxycorticosterone (DOC) response to exogenous ovine CRH (1.0 µg/kg) administration. The DOC response is summarized across the experimental phases by area under the curve (A). DOC concentrations for each timepoint sampled during baseline (B), induction (C), and self-administration (D) are shown. Symbols represent significant differences when compared to baseline (t = −15min). Animals are uniquely colored. ap < 0.05, *p < 0.01, **p < 0.001.
