Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Sequence alignment of melanocortin (MC) peptides. All MCs share the conserved –M–X–H–F–R–W– motif, which serves as the pharmacophore for receptor binding (8, 10). The –K–K–R–R–P– motif within adrenocorticotropic hormone (ACTH) is considered the second pharmacophore and is required for successful activation of adrenocorticotropic hormone receptor (26).
