Figure 1.

Time‐dependent uptake of serotonin, dopamine, noradrenaline, and histamine for (A) mOct2, (B) mOct3, and (C) mPmat. Time‐dependent monoamine transport assays were conducted in CHO‐K1 cells stably overexpressing mOct2, mOct3, or mPmat or control cells. Cells were incubated in the presence of 100 μm serotonin, dopamine, noradrenaline, or histamine for 2–60 min at 37 °C. Individual transport assays were performed in triplicate (three wells were analyzed for each group per trial). The results were confirmed at least two times in separate experiments using different cryopreserved cell vials. The results shown are representative of experiments performed.