Figure 2. Identification and functional analysis of global proteomics in gastric cancer.

(a) Venn diagram illustrating differentially expressed proteins in each pair of samples. GO and KEGG pathway functional enrichment of (b) down- and (c) up-regulated proteins are examined. (d) Up- and down-regulated proteins in each pair (tumor vs. normal) are clustered by enriched functional terms discovered in (b) and (c). Functional enrichment clusters in different biological categories including nucleus, mitochondrion, catabolic process and ATPase are highlighted.