Table 1. Top ten differentially up- and down-regulated lysine succinylation sites.
| Gene Name | UniProt Accession | Ksucc Position | MaxQuant Score | Modified sequence | Log2 C/N Ratio | Regulation |
|---|---|---|---|---|---|---|
| STAT1 | P42224 | 279 | 93.649 | _K(su)LEELEQK_ | 1.614 | up |
| EPCAM | P16422 | 129 | 109.07 | _RTDK(su)DTEITCSER_ | 1.491 | up |
| SFN | P31947 | 77 | 120.63 | _SNEEGSEEK(su)GPEVR_ | 1.198 | up |
| OAS2 | P29728 | 239 | 63.091 | _K(su)DNFDIAEGVR_ | 1.054 | up |
| GBP1 | P32455 | 487 | 63.624 | _EK(su)EIEVER_ | 1.051 | up |
| ALDH18A1 | P54886 | 409 | 72.34 | _K(su)DLEEAEGR_ | 0.899 | up |
| POR | P16435 | 291 | 56.916 | _K(su)LNQGTER_ | 0.816 | up |
| EEF1G | P26641 | 243 | 63.565 | _QK(su)PQAER_ | 0.787 | up |
| HSP90AB1 | P08238 | 550 | 112.44 | _EGLELPEDEEEK(su)K_ | 0.644 | up |
| CALD1 | Q05682 | 569 | 128.06 | _QQEAALELEELK(su)K_ | −1.112 | down |
| DYNC1H1 | Q14204 | 3284 | 124.29 | _EDLDK(su)VEPAVIEAQNAVK_ | −1.184 | down |
| ANXA6 | P08133 | 478 | 119.39 | _AINEAYK(su)EDYHK_ | −1.210 | down |
| TXNL1 | O43396 | 226 | 120.33 | _SEPTQALELTEDDIK(su)EDGIVPLR_ | −1.244 | down |
| FLNA | P21333 | 865 | 66.989 | _VK(su)VEPSHDASK_ | −1.312 | down |
| COL6A3 | P12111 | 869 | 119.96 | _IIDELNVK(su)PEGTR_ | −1.427 | down |
| TAGLN | Q01995 | 21 | 144.65 | _K(su)YDEELEER_ | −1.662 | down |
| VCL | P18206 | 387 | 90.475 | _K(su)IDAAQNWLADPNGGPEGEEQIR_ | −1.809 | down |
| HSP90B1 | P14625 | 800 | 98.582 | _ESTAEK(su)DEL_ | −2.170 | down |
| MYH11 | P35749 | 1499 | 117 | _ALEEALEAK(su)EELER_ | −2.437 | down |