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. 2017 Feb 6;7:38105. doi: 10.1038/srep38105

Figure 1. Lactic acid induces erythroid differentiation of K562 cells.

Figure 1

(a) Haemoglobin and CD235a mRNA expression levels in K562 cells 72 hours after 10-mM lactic acid treatment. mRNA levels were normalized to the expression of β-actin mRNA. *P < 0.05 vs. their respective controls. (b) Haemoglobin expression in K562 cells at 72 hours after treatment with 5-, 7.5- or 10-mM lactic acid. (c) Flow cytometry demonstrates that CD235a expression in the K562 cells increased 3 days after lactic acid treatment. Mean fluorescence intensity (MFI) analyses are shown. *P < 0.05.