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. Author manuscript; available in PMC: 2017 Feb 18.
Published in final edited form as: N Engl J Med. 2016 Aug 18;375(7):655–665. doi: 10.1056/NEJMsa1507092

Figure 1. Genetic Variants Associated with Hypertrophic Cardiomyopathy.

Figure 1

Panel A shows variants associated with hypertrophic cardiomyopathy that are overrepresented in the general population. The five highest-frequency variants account for 74% of the misclassified variation in the general population. Panel B shows the minor-allele genotype frequencies for high-frequency variants associated with hypertrophic cardiomyopathy; all variants are significantly more common among black Americans than among white Americans (P<0.001 by the chi-square test for all five variants).