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. 2017 Feb 6;7:42016. doi: 10.1038/srep42016

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Copyright © 2017, The Author(s)

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Mortalin-overexpressing MCF-7 cells showed higher expression of cancer stem cell marker proteins, ABCG2, OCT-4, as determined by Western blotting (A) and high degree of spheroid formation (B). FACS and RT-qPCR analyses revealed higher level of CD44 (C), CD9, MRP1, CD133 and ALDH1 (D) expression and low level of CD24 (C,D) and CD61 (D) expression in mortalin-overexpressing cells as compared to the control.